β4 integrin in hereditary and acquired mucocutaneous diseases
نویسندگان
چکیده
منابع مشابه
A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4
Increased integrin β4 (ITGB4) level is accompanied by malignant progression of multiple carcinomas. However, selective therapeutic strategies against cancer cells expressing a high level of ITGB4 have not been reported. Here, for the first time, we report that a chiral small molecule, SEC, selectively promotes apoptosis in cancer cells expressing a high level of ITGB4 by inducing ITGB4 nuclear ...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2016
ISSN: 0906-6705
DOI: 10.1111/exd.12961